Semi-quantitative and quantitative dynamic contrast-enhanced (DCE) MRI parameters as prostate cancer imaging biomarkers for biologically targeted radiation therapy.
Hayley M ReynoldsSirisha TadimallaYu-Feng WangMaryam MontazerolghaemYu SunScott WilliamsCatherine MitchellMary E FinneganDeclan G MurphyAnnette HaworthPublished in: Cancer imaging : the official publication of the International Cancer Imaging Society (2022)
Incorporating DCE MRI parameters with DWI and T2w gives improved accuracy for tumour detection at a voxel level. DCE MRI parameters should be used to spatially characterise tumour biology for biologically targeted radiation therapy treatment planning.
Keyphrases
- contrast enhanced
- diffusion weighted
- radiation therapy
- diffusion weighted imaging
- magnetic resonance imaging
- prostate cancer
- high resolution
- magnetic resonance
- computed tomography
- cancer therapy
- radical prostatectomy
- squamous cell carcinoma
- radiation induced
- photodynamic therapy
- loop mediated isothermal amplification
- sensitive detection
- real time pcr