Prospective analysis of clinically significant prostate cancer detection with [18F]DCFPyL PET/MRI compared to multiparametric MRI: a comparison with the histopathology in the radical prostatectomy specimen, the ProStaPET study.
Yves J L BodarBen G J C ZwezerijnenPatrick J van der VoornBernard H E JansenRuth S SmitSabrine Q KolDennie MeijerKatelijne de BieMaqsood YaqubBert A D WindhorstHarry N H HendrikseAndré N VisDaniela E Oprea-LagerPublished in: European journal of nuclear medicine and molecular imaging (2021)
Both [18F]DCFPyL-PET/MRI and mpMRI were only partly able to detect csPCa on a per-segment basis. An accurate detection (90.0%) of the highest GG lesion at patient-level was observed when comparing both [18F]DCFPyL-PET/MRI and mpMRI biopsy advice with the histopathology in the RARP specimen. So, despite the finding that [18F]DCFPyL-PET/MRI adequately detects csPCa, it does not outperform mpMRI.