Laxative Use and Risk of Dyskalemia in Patients with Advanced CKD Transitioning to Dialysis.

Keiichi Sumida Ankur A Dashputre Praveen K Potukuchi Fridtjof Thomas Yoshitsugu Obi Miklos Z MolnarJustin D GatwoodElani StrejaKamyar Kalantar-ZadehCsaba Pal Kovesdy

Published in: Journal of the American Society of Nephrology : JASN (2021)

Laxative use was independently associated with lower risk of hyperkalemia during the last 1-year pre-ESKD period. Our findings support a putative role of constipation in potassium disarrays and also support (with a careful consideration for the risk-benefit profiles) the therapeutic potential of laxatives in hyperkalemia management in advanced CKD.

Keyphrases

chronic kidney disease
end stage renal disease
irritable bowel syndrome
peritoneal dialysis