Diabetes type 2 risk gene Dusp8 is associated with altered sucrose reward behavior in mice and humans.

Peter BaumannSonja C SchrieverStephanie KullmannAnnemarie ZimprichAndreas PeterValerie Gailus-DurnerHelmut FuchsMartin Hrabe de AngelisWolfgang WurstMatthias H TschöpMartin Heni Sabine Maria Hölter Paul Thomas Pfluger

Published in: Brain and behavior (2020)

Our data suggest a novel role for Dusp8 in the perception of sweet high caloric food as well as in the control of sucrose consumption and foraging in mice and humans.

Keyphrases

high fat diet induced
type diabetes
cardiovascular disease
electronic health record
genome wide
copy number
skeletal muscle
human health
climate change
transcription factor