Single Nucleotide Polymorphisms and Post-operative Complications Following Major Gastrointestinal Surgery: a Systematic Review and Meta-analysis.

Joseph BeechamAndrew HartLeo AlexandreJames HernonBhaskar KumarStephen Lam

Published in: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract (2019)

We found biologically plausible associations between SNPs involved in inflammation and post-operative infection, but the available data were too limited and of insufficient quality to reach definitive conclusions. Further work is needed, including genome-wide association studies (GWAS).

Keyphrases

genome wide association
minimally invasive
coronary artery bypass
oxidative stress
electronic health record
risk factors
big data
case control
locally advanced
quality improvement
radiation therapy
percutaneous coronary intervention