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Long-term hepatic function of patients with compensated cirrhosis following successful direct-acting antiviral treatment for hepatitis C virus infection.

Eiichi OgawaAkira KawanoAritsune OohoNorihiro FurusyoTakeaki SatohKazuhiro TakahashiEiji KajiwaraKazufumi DohmenMakoto NakamutaKoichi AzumaToshimasa KoyanagiNobuyuki YamashitaKimihiko YanagitaYasunori IchikiMasami KuniyoshiNaoki YamashitaChie MoritaRie SugimotoMasaki KatoShinji ShimodaHideyuki NomuraJun Hayashinull null
Published in: Journal of gastroenterology and hepatology (2021)
In a large real-world cohort of patients with compensated cirrhosis treated with a DAA, remarkable improvement in hepatic function was seen after HCV cure, especially during the first year after the end of treatment. Treatment in the early stage of cirrhosis would be of great benefit for preventing liver deterioration to decompensation.
Keyphrases
  • hepatitis c virus
  • human immunodeficiency virus
  • combination therapy
  • newly diagnosed