Iridium-catalyzed selective amination of B(4)-H for the synthesis of o -carborane-fused indolines.

An iridium-catalyzed selective amination of B(4)-H via dehydrogenative cross-coupling of B-H/N-H bonds for the synthesis of o -carborane-fused indolines has been developed for the first time. Various types of unprecedented o -carborane-fused indolines have been synthesized, which would be potential candidates for applications in drug discovery, pharmaceutical chemistry and functional materials. This work offers a valuable reference for the designing and synthesis of o -carborane-fused heterocycles.