Phenytoin Is Promoting the Differentiation of Dental Pulp Stem Cells into the Direction of Odontogenesis/Osteogenesis by Activating BMP4/Smad Pathway.

Published in: Disease markers (2022)

Phenytoin has the ability of promoting the differentiation of hDPSC into odontoblasts and osteoblasts. BMP4/Smad pathway, inducing odontogenic/osteogenic differentiation of hDPSC, appears a main process in this context.

Keyphrases

stem cells
epithelial mesenchymal transition
bone regeneration
mesenchymal stem cells
transforming growth factor
cell therapy