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The impact of unilateral pulmonary artery stenosis on right ventricular to pulmonary arterial coupling in patients with transposition of the great arteries.

Renée S JoosenMichiel VoskuilGregor J KringsM Louis HandokoMichael G DickinsonMarielle C van de VeerdonkJohannes M P J Breur
Published in: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions (2024)
Unilateral PA stenosis results in an increased RV afterload in TGA patients after ASO. RV remodeling and function remain within normal limits when analyzed by CMR but RV pressure-volume loop analysis shows impaired RV diastolic stiffness and RV contractility leading to RV-PA uncoupling.
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