Tropism of Newcastle disease virus strains for chicken neurons, astrocytes, oligodendrocytes, and microglia.

Salman L ButtVeridiana Maria Brianezi Dignani MouraLeonardo SustaPatti J MillerJessica M HutchesonStivalis Cardenas-GarciaCorrie C BrownFranklin D WestClaudio L AfonsoJames B Stanton

Published in: BMC veterinary research (2019)

These data indicate that similar to other paramyxoviruses, neurons and glial cells (astrocytes, oligodendrocytes, and microglia) are susceptible to vNDV infection, and suggest that factors other than cellular tropism are likely the major determinant of the neurotropic phenotype.

Keyphrases

disease virus
neuropathic pain
spinal cord
induced apoptosis
inflammatory response
cell cycle arrest
escherichia coli
spinal cord injury
electronic health record
big data
cell death
oxidative stress
pi k akt