A case series of pediatric survivors of anaplastic pleomorphic xanthoastrocytoma.
Rebecca RonsleyChristopher DunhamStephen YipLindsay BrownJeffrey A ZuccatoShirin KarimiGelareh ZadehKaren GoddardAsh SinghalJuliette HukinSylvia ChengPublished in: Neuro-oncology advances (2021)
The natural history and optimal treatment of this rare pediatric tumor are not well understood. This case series supports the use of adjuvant chemoradiotherapy in the treatment of APXA. The genetic landscape may be informative for optimizing treatment and prognosis.