Peptidorhamnomannan from Lomentospora prolificans modulates the inflammatory response in macrophages infected with Candida albicans.
Mariana Ingrid Dutra da Silva XistoSuelen S SantosLuana RossatoFábio Seiti Yamada YoshikawaRosa Maria Tavares HaidoSandro Rogério de AlmeidaEliana Barreto-BergterPublished in: BMC microbiology (2020)
We suggest that peptidorhamnomannan acts as a molecular pattern on the invading pathogen, promotes TNF-α production and, thus, increases macrophage fungicidal activity against Candida albicans.