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Sensitization to peanut, egg or pets is associated with skin barrier dysfunction in children with atopic dermatitis.

Michael G SherenianArjun KothariJocelyn M BiaginiJohn W KronerAsel Baatyrbek KyzyElisabet JohannsonGowtham AtluriHua HeLisa J MartinGurjit K Khurana Hershey
Published in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2021)
In this largely clinic-based cohort of young children with AD, allergic sensitization to peanut, egg, cat or dog was associated with more severe disease and skin barrier function but not markers of cutaneous inflammation. These data need replicating in a population-based cohort but may have important implications for understanding the interaction between AD and allergic sensitization.
Keyphrases
  • atopic dermatitis
  • oxidative stress
  • soft tissue
  • wound healing
  • young adults
  • primary care
  • allergic rhinitis
  • electronic health record
  • early onset
  • machine learning
  • deep learning