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The Effect of Rosmarinic Acid on Apoptosis and nNOS Immunoreactivity Following Intrahippocampal Kainic Acid Injections in Rats.

Safoura KhamseSeyed Shahabeddin SadrMehrdad RoghaniMina RashvandMaryam MohammadianNarges MarefatiElham HaratiFatemeh Ebrahimi
Published in: Basic and clinical neuroscience (2020)
RA had neuroprotective effects, compared to KA, through reduced apoptosis and nNOS-positive neurons, but not MAPK and COX-2.
Keyphrases
  • oxidative stress
  • cell cycle arrest
  • endoplasmic reticulum stress
  • cell death
  • nitric oxide synthase
  • pi k akt
  • signaling pathway
  • rheumatoid arthritis
  • disease activity
  • ankylosing spondylitis