Interplay between Tumor Mutational Burden and Mutational Profile and Its Effect on Overall Survival: A Pilot Study of Metastatic Patients Treated with Immune Checkpoint Inhibitors.
Camila Bragança XavierCarlos Diego H LopesBeatriz M AwniEduardo F CamposJoão Pedro B AlvesAnamaria Aranha CamargoGabriela D A GuardiaPedro Alexandre Favoretto GalanteDenis Leonardo Fontes JardimPublished in: Cancers (2022)
Combining TMB and mutation profiles in key cancer genes can better qualify patients for ICI treatment and predict their OS.
Keyphrases
- end stage renal disease
- ejection fraction
- chronic kidney disease
- newly diagnosed
- squamous cell carcinoma
- small cell lung cancer
- papillary thyroid
- peritoneal dialysis
- gene expression
- risk factors
- patient reported outcomes
- dna methylation
- combination therapy
- replacement therapy
- patient reported
- free survival
- childhood cancer