Macrophage-derived exosomes attenuate fibrosis in airway epithelial cells through delivery of antifibrotic miR-142-3p.
Julien GuiotMaureen CambierAmandine BoeckxMonique HenketOlivier NivellesFanny GesterEdouard LouisMichel MalaiseFranck DequiedtRenaud LouisIngrid StrumanMakon-Sébastien NjockPublished in: Thorax (2020)
Our results suggest that macrophage-derived exosomes may fight against pulmonary fibrosis progression via the delivery of antifibrotic miR-142-3 p to alveolar epithelial cells and lung fibroblasts.