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Gut microbial characteristics in poor appetite and undernutrition: a cohort of older adults and microbiota transfer in germ-free mice.

Kristina S FluitmanMark DavidsLouise E OlofssonMadelief WijdeveldValentina TremaroliBart J F KeijserMarjolein VisserFredrik BäckhedMax NieuwdorpRichard G IJzerman
Published in: Journal of cachexia, sarcopenia and muscle (2022)
This study demonstrates several associations of the gut microbiota with both poor appetite and undernutrition in older adults. Moreover, it is the first to explore a causal relation between the aged gut microbiota and body weight and body composition in the host. Possibly, microbiota-manipulating strategies will benefit older adults prone to undernutrition.
Keyphrases
  • body weight
  • body composition
  • physical activity
  • resistance training
  • weight loss
  • bone mineral density
  • metabolic syndrome
  • high fat diet induced
  • adipose tissue
  • skeletal muscle