Relationship between immune status after ATG treatment and PNH clone evolution in patients with severe aplastic anemia.

Honglei WangHui LiuTing WangLijuan LiChunyan LiuLiyan LiTong ChenWeiwei QiKai DingRong Fu

Published in: Journal of clinical laboratory analysis (2020)

In SAA patients with PNH clones, the cytotoxic T-cell function and Th1 cell number recovered more quickly and had better response to IST. A small number of SAA patients with or without PNH clones developed MDS malignant clones.

Keyphrases

single cell
cell therapy
allogeneic hematopoietic stem cell transplantation
stem cells
iron deficiency
mesenchymal stem cells
drug induced
replacement therapy