No effect of platelet-rich plasma as adjuvant to bone marrow stimulation for the treatment of chondral defects in a large animal model.

Morten Lykke OlesenBjørn Borsøe ChristensenCasper Bindzus FoldagerKris Chadwick HedeNatasja Leth BergholtMartin C Lind

Published in: Archives of orthopaedic and trauma surgery (2019)

Four repeated local injections of leukocyte-rich PRP after BMS in the treatment of full-thickness cartilage injuries demonstrated no beneficial effects in terms of macroscopic and histological cartilage repair tissue quality.

Keyphrases

platelet rich plasma
bone marrow
early stage
mesenchymal stem cells
extracellular matrix
optical coherence tomography
quality improvement
combination therapy
replacement therapy