Biological effect of tissue plasminogen activator (t-PA) and DNase intrapleural delivery in pleural infection patients.
Nikolaos I KanellakisJohn M WrightsonRobert HallifaxEihab O BedawiRachel MercerMaged HassanRachelle AsciakEmma HedleyMelissa DobsonTao DongIoannis PsallidasNajib M RahmanPublished in: BMJ open respiratory research (2019)
We conclude that the PF volume drainage increment seen with the administration of t-PA does not appear to act solely via activation of the MCP-1 pathway.