Epigenetic Biomarkers of Prenatal Tobacco Smoke Exposure Are Associated with Gene Deletions in Childhood Acute Lymphoblastic Leukemia.

Keren XuShaobo LiTodd P WhiteheadPriyatama PandeyAlice Y KangLibby M Morimoto Scott C Kogan Catherine Metayer Joseph L WiemelsAdam J de Smith

Published in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2021)

Analyses of deletion breakpoint sequences are required to further understand the mutagenic effects of tobacco smoke in childhood ALL.

Keyphrases

acute lymphoblastic leukemia
early life
dna methylation
pregnant women
childhood cancer
gene expression
genome wide
copy number
allogeneic hematopoietic stem cell transplantation