The BR-body proteome contains a complex network of protein-protein and protein-RNA interactions.

V Nandana I W Rathnayaka-Mudiyanselage Nisansala S MuthunayakeA HatamiC B MousseauL A Ortiz-Rodr GuezJ VaishnavM CollinsA GegaK S MallikaarachchiH YassineA GhoshJ S BiteenY ZhuM M ChampionW Seth Childers Jared M Schrader

Published in: bioRxiv : the preprint server for biology (2023)

BR-body proteomics identified 111 proteins enriched in BR-bodies.BR-bodies associate with an interconnected network of RNP condensates.BR-body condensation is modulated by its interaction network.RNA is required for rapid BR-body condensation.

Keyphrases

protein protein
small molecule
mass spectrometry
network analysis
quantum dots