Furosemide attenuates tubulointerstitial injury and allows functional testing of porcine kidneys during normothermic machine perfusion.
Baran OgurluTim L HamelinkVeerle A LantingaHendrik Gerrit Derk LeuveninkMerel B F PoolCyril MoersPublished in: Artificial organs (2024)
This study showed that the addition of furosemide affected renal function while attenuating tubulointerstitial injury during NMP. Therefore, furosemide supplementation may provide renal protection and serve as a functional test for pretransplant kidney viability assessment during NMP.