A (fire)cloud-based DNA methylation data preprocessing and quality control platform.

Divy KangeyanAndrew DunfordSowmya IyerChip StewartMegan HannaGad GetzMartin J Aryee

Published in: BMC bioinformatics (2019)

The workflows produce data quality metrics, visualization tracks, and aggregated output for further downstream analysis. Optional use of cloud computing resources facilitates analysis of large datasets, and integration with existing methylome profiles. The workflow design principles are applicable to other genomic data types.

Keyphrases

electronic health record
quality control
dna methylation
big data
gene expression
machine learning
copy number
quality improvement