Prevalence of Epstein-Barr Virus Infection and Mismatch Repair Protein Deficiency and the Correlation of Immune Markers in Tibetan Patients with Gastric Cancer.
Jie ShiXu YangXinmei WangYufeng LuoWeixun ZhouHanhuan LuoZhaxi BianbaZhuoma NimaQian WangHan WangRuiqian LiaoQuzhen CirenMei LiJunyi PangPublished in: BioMed research international (2022)
In Tibetan GC patients, the rates of EBV infection, dMMR, and positive PD-L1 expression were 9.17%, 5%, and 32.5%, respectively. EBV infection was associated with the numbers of CD3+ T cells and CD8+ T cells and PD-L1 expression within the tumor. These markers may guide the selection of Tibetan GC patients for immunotherapy.