Complete metabolic response with [18 F]fluorodeoxyglucose-positron emission tomography/computed tomography predicts survival following induction chemotherapy and radical cystectomy in clinically lymph node positive bladder cancer.
Johan AbrahamssonPetter KollbergHelen AlmquistMats BläckbergJohan BrändstedtKerstin LyttkensAthanasios SimoulisGottfrid SjödahlAnne SörenbyElin TrägårdhFredrik LiedbergPublished in: BJU international (2021)
Complete metabolic response with FDG-PET-CT predicts survival after induction chemotherapy followed by RC in patients with LN-positive bladder cancer and comprises a novel tool in evaluating response to chemotherapy before surgery. This strategy has the potential to tailor treatment in individual patients by identifying significant response to chemotherapy, which motivates the administration of a full course of induction chemotherapy with a higher threshold for suspending treatment due to toxicity and side-effects.
Keyphrases
- positron emission tomography
- computed tomography
- locally advanced
- lymph node
- end stage renal disease
- magnetic resonance imaging
- pet ct
- squamous cell carcinoma
- neoadjuvant chemotherapy
- minimally invasive
- chronic kidney disease
- newly diagnosed
- rectal cancer
- peritoneal dialysis
- chemotherapy induced
- early stage
- pet imaging
- prognostic factors
- coronary artery disease
- patient reported outcomes
- contrast enhanced
- smoking cessation