Overexpression of MiR-29b-3p Inhibits Atrial Remodeling in Rats by Targeting PDGF-B Signaling Pathway.

Xiangwei LvPan LuYisen HuTong-Tong Xu

Published in: Oxidative medicine and cellular longevity (2021)

MiR-29b-3p was able to reduce atrial structural and electrical remodeling in the study's rat fibrosis model. This biological function may be expressed through the targeted regulation of the PDGF-B signaling pathway.

Keyphrases

signaling pathway
pi k akt
atrial fibrillation
smooth muscle
epithelial mesenchymal transition
vascular smooth muscle cells
left atrial
cell proliferation
induced apoptosis
oxidative stress
transcription factor
left ventricular
angiotensin ii
endoplasmic reticulum stress