Combining multivariate genomic approaches to elucidate the comorbidity between autism spectrum disorder and attention deficit hyperactivity disorder.

Peyre Hugo Tabea Schoeler Chao-Yu Liu Camille Michèle Williams Nicolas Hoertel Karoline Alexandra Havdahl Jean-Baptiste Pingault

Published in: Journal of child psychology and psychiatry, and allied disciplines (2021)

Using multivariate genomic analyses, the present study uncovers shared and specific genetic variants associated with ASD and ADHD. Further functional investigation of genes mapped to those shared variants may help identify pathophysiological pathways and new targets for treatment.

Keyphrases

attention deficit hyperactivity disorder
autism spectrum disorder
copy number
intellectual disability
genome wide
data analysis
dna methylation
gene expression