PNPLA3 risk allele is associated with risk of hepatocellular carcinoma but not decompensation in compensated cirrhosis.
Esteban UriasNicholas R TedescoDaniel A BurkholderIsabel J MoranMatthew J MillerVenkata Sai J JastySnehal PatilSebastian ZoellnerKarn WijarnpreechaVincent L ChenPublished in: Hepatology communications (2024)
The PNPLA3-rs738409-G allele is associated with an increased risk of HCC among patients with baseline compensated cirrhosis. People with cirrhosis and PNPLA3-rs738409-GG genotype may warrant more intensive HCC surveillance.
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