Radiation pneumonitis in lung cancer patients treated with chemoradiation plus durvalumab.

Narek ShaverdianMaria ThorAnnemarie F ShepherdMichael D OffinAndrew JacksonAbraham J WuDaphna Y GelblumEllen D YorkeCharles B Simone IiJamie E ChaftMatthew D HellmannDaniel R GomezAndreas RimnerJoseph O Deasy

Published in: Cancer medicine (2020)

Our data suggest a delayed onset of RP in patients treated with cCRT and durvalumab vs cCRT alone, and for RP to develop in a greater number of patients treated with cCRT and durvalumab. Previously published RP models significantly underestimate the rate of symptomatic RP among patients treated with cCRT and durvalumab.

Keyphrases

rectal cancer
electronic health record
radiation therapy
locally advanced
machine learning
idiopathic pulmonary fibrosis