TIR-Domain-Containing Adapter-Inducing Interferon-β (TRIF) Regulates CXCR5+ T helper Cells in the Intestine.

Saravana KanagaveluClaudia FloresShinichiro HagiwaraJose RuizJinhee HyunEi E ChoFrank SunLaura RomeroDavid Q ShihMasayuki Fukata

Published in: Journal of clinical & cellular immunology (2016)

Our results reveal a novel role of TRIF in the regulation of humoral immunity in the intestine that can be utilized as a basis for a unique vaccine strategy.

Keyphrases

induced apoptosis
dendritic cells
immune response
cell cycle arrest
regulatory t cells
genome wide
single cell
endoplasmic reticulum stress
oxidative stress
gene expression
dna methylation
cell proliferation
pi k akt