Adverse Drug Reactions to Opioids: A Study in a National Pharmacovigilance Database.

Moa Gustafsson Cristiano Matos João Joaquim Joep H G Scholl Florence P A M van Hunsel

Published in: Drug safety (2023)

Patients treated with opioids experienced ADRs, primarily nausea, dizziness, and vomiting. For those groups of drugs, no significant differences were found between the sexes, except for the vomiting associated with tramadol. In general, ADRs related to opioids presented higher RORs when uncorrected and corrected for sexes and expenditure than other drugs. There was more disproportionate reporting for ADRs concerning abuse, misuse, and medication errors for opioids than other drugs in the Dutch SRS.

Keyphrases

adverse drug
chronic pain
pain management
drug induced
chemotherapy induced
electronic health record
emergency department
quality improvement
abdominal pain
patient safety