Saliva-based cell-free DNA and cell-free mitochondrial DNA in head and neck cancers have promising screening and early detection role.

Lana SayalOmar HamadahAroub AlMasri Majdy Idrees Peter J Thomson Omar Kujan

Published in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (2022)

cfDNA and cf-mtDNA showed potential for use as precision medicine tools to detect HNSCC. Further multi-centre prospective studies are warranted to assess the prognostic utility of these molecules.

Keyphrases

mitochondrial dna
cell free
copy number
cystic fibrosis
circulating tumor
case control
human health
gene expression
risk assessment
young adults
climate change