The importance of confirmatory assays in testing blood donors for human T-cell lymphotropic virus.
Marina Lobato MartinsEdel Figueiredo Barbosa-StancioliMaria Clara Fernandes da Silva-MaltaSônia Mara NunesPublished in: Vox sanguinis (2024)
The use of the Alinity assay reduced the frequency of false-positive results. Confirmatory tests are important to identify true HTLV infection in blood donors, because more than 58% of initially reactive individuals are confirmed as seronegative. Categorizing S/CO values is useful for assessing the likelihood of true HTLV-1/2 infection.
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