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Does the FSHB c.-211G>T polymorphism impact Sertoli cell number and the spermatogenic potential in infertile patients?

Maria SchubertSophie KaldeweyLina Pérez LanuzaHenrike KrenzMartin DugasSven BerresSabine KlieschJoachim WistubaJörg Gromoll
Published in: Andrology (2020)
The FSHB c.-211G>T polymorphism does not affect SC numbers or SCWL, thereby in principle maintaining the spermatogenic potential. The previously observed clinical phenotype for the FSHB genotype might therefore be caused by a hypo-stimulated spermatogenesis and not due to a decreased SC number.
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