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Polycaprolactone/Gelatin/Hydroxyapatite Electrospun Nanomembrane Materials Incorporated with Different Proportions of Attapulgite Synergistically Promote Bone Formation.

Jun LiuSiyu WuJiayi MaChun LiuTing DaiXiaoyu WuHongbin ZhaoDong Zhou
Published in: International journal of nanomedicine (2022)
This study clarified for the first time that the combination of HA and ATP orchestrated biomaterial-induced osseointegration, and the synergistic effect was more significant when the ratio of ATP/HA was 2:1. This conclusion also provides new ideas and a scientific basis for the development of functionalized nanomaterials in bone tissue engineering.
Keyphrases
  • tissue engineering
  • high glucose
  • bone mineral density
  • diabetic rats
  • bone regeneration
  • endothelial cells
  • soft tissue
  • molecularly imprinted
  • high resolution