Response of bilateral Wilms tumor to chemotherapy suggests histologic subtype and guides treatment.
Colton DuncanSuraj Sarvode MothiTeresa C SantiagoJordan A CogginsDylan E GraetzMichael W BishopElizabeth A MullenAndrew J MurphyDaniel M GreenMatthew J KrasinAndrew M DavidoffPublished in: Journal of the National Cancer Institute (2024)
Tumors that increased in size during neoadjuvant chemotherapy were most frequently stromal-predominant bilateral Wilms tumor, especially in younger patients. Therefore, nephron-sparing surgery, rather than biopsy, or extension or intensification of neoadjuvant chemotherapy, should be considered for bilateral Wilms tumors that increase in volume during neoadjuvant chemotherapy, particularly in patients aged younger than 18 months.
Keyphrases
- neoadjuvant chemotherapy
- locally advanced
- lymph node
- end stage renal disease
- sentinel lymph node
- ejection fraction
- newly diagnosed
- chronic kidney disease
- rectal cancer
- squamous cell carcinoma
- prognostic factors
- radiation therapy
- case report
- atrial fibrillation
- coronary artery disease
- coronary artery bypass
- ultrasound guided
- replacement therapy