Early menarche is associated with insulin-resistance and non-alcoholic fatty liver disease in adolescents with obesity.

Anna Di SessaAnna GrandonePierluigi MarzuilloGiuseppina Rosaria UmanoGrazia CirilloEmanuele Miraglia Del Giudice

Published in: Journal of pediatric endocrinology & metabolism : JPEM (2021)

Girls with obesity presenting early menarche showed higher HOMA-IR levels, lower Matsuda Index and IGI values, and higher risk of NAFLD compared to girls without early menarche.

Keyphrases

insulin resistance
metabolic syndrome
type diabetes
high fat diet induced
weight loss
young adults
physical activity
weight gain
body mass index
liver fibrosis