Characterization of an N-terminal Nav1.5 channel variant - a potential risk factor for arrhythmias and sudden death?

Stefanie Scheiper-WellingPaolo ZuccoliniOliver RauhBritt-Maria BeckmannChristof GeisenAnna MoroniGerhard ThielSilke Kauferstein

Published in: BMC medical genetics (2020)

The results support the assumption that the detected sequence aberration alters Nav1.5 channel function and may predispose to cardiac arrhythmias and sudden cardiac death.

Keyphrases

congenital heart disease
left ventricular
heart failure
risk assessment
amino acid