Transcriptional and Immune Landscape of Cardiac Sarcoidosis.

Jing Liu Pan Ma Lulu LaiAna VillanuevaAndrew L Koenig Gregory R BeanDawn E BowlesCarolyn GlassMichael Watson Kory J Lavine Chieh-Yu Lin

Published in: Circulation research (2022)

In this study, we identified diverse populations of immune cells with distinct molecular signatures that comprise the sarcoid granuloma. These findings provide new insights into the pathology of cardiac sarcoidosis and highlight opportunities to improve diagnostic testing.

Keyphrases

left ventricular
gene expression
transcription factor
genome wide
single cell
oxidative stress
atrial fibrillation
heat shock