Free 25-hydroxyvitamin D is low in obesity, but there are no adverse associations with bone health.

Jennifer S WalshAmy L EvansSimon BowlesKim E NaylorKerry S JonesInez SchoenmakersRichard M JacquesRichard Eastell

Published in: The American journal of clinical nutrition (2016)

Total and free 25(OH)D and 1,25(OH)2D are lower at higher BMI, which cannot be explained by lower DBP or the shorter half-life of 25(OH)D3 We speculate that low 25(OH)D in obesity is due to a greater pool of distribution. Lower 25(OH)D may not reflect at-risk skeletal health in obese people, and BMI should be considered when interpreting serum 25(OH)D as a marker of vitamin D status.

Keyphrases

weight loss
weight gain
metabolic syndrome
public health
insulin resistance
type diabetes
healthcare
body mass index
mental health
high fat diet induced
adipose tissue
health information
bariatric surgery
emergency department
soft tissue
bone regeneration
bone loss