Microstructural Changes in the Cerebral White Matter After 12 Months of CPAP Treatment for Moderate to Severe Obstructive Sleep Apnoea: A TBSS Study.

Xiang LiuZhipeng WeiLong TingXuming LiuYongqiang ShuHuang LingLifeng LiYumeng LiuGuojin XiaDechang PengHaijun Li

Published in: Nature and science of sleep (2024)

Our results suggest that reversible recovery of reduced brain WM integrity due to OSA may require longer CPAP treatment. Moreover, changes in the integrity of the commissural fibers were associated with emotion regulation. These restored WM areas may explain the cognitive and mood improvements observed after OSA treatment.

Keyphrases

white matter
obstructive sleep apnea
positive airway pressure
sleep apnea
early onset