Monitoring of tumor burden in vivo by optical imaging in a xenograft SCID mouse model: evaluation of two fluorescent proteins of the GFP-superfamily.

Ingrid B BoehmStephan GehrkeBeate KlebMartin HungerbühlerRolf MüllerKlaus J KloseHeiko Alfke

Published in: Acta radiologica (Stockholm, Sweden : 1987) (2018)

We established an in vivo xenograft mouse model (DsRed-MeWo) that is reliable, reproducible, and superior to the EGFP model as a preclinical tool to study innovative therapies by FRI under real-time in vivo conditions.

Keyphrases

mouse model
high resolution
high speed
living cells
cell therapy
risk factors
mass spectrometry
mesenchymal stem cells
label free
single molecule