Robust data-driven identification of risk factors and their interactions: A simulation and a study of parental and demographic risk factors for schizophrenia.

David GyllenbergIan W McKeagueAndre SouranderAlan S Brown

Published in: International journal of methods in psychiatric research (2020)

We have provided an analytic pipeline for data-driven identification of main and interaction effects in case-control data. We identified highly replicated main effects for schizophrenia, but no interactions.

Keyphrases

risk factors
bipolar disorder
case control
electronic health record
deep learning