Cooperation of MLL1 and Jun in controlling H3K4me3 on enhancers in colorectal cancer.

Xiang LinJi-Dong ChenChen-Yu WangZhen CaiRui ZhanChen YangLa-Ying ZhangLian-Yun LiYong XiaoMing-Kai ChenMin Wu

Published in: Genome biology (2023)

Taken together, our study illustrates the genome-wide landscape and the regulatory mechanisms of m3Es in CRC, and reveals potential novel strategies for cancer treatment.

Keyphrases

genome wide
dna methylation
acute myeloid leukemia
transcription factor
single cell
gene expression
small molecule
risk assessment
climate change
human health