Machine-learning-based approach for predicting response to anti-calcitonin gene-related peptide (CGRP) receptor or ligand antibody treatment in patients with migraine: A multicenter Spanish study.

Alicia Gonzalez-MartinezJosué PagánAncor Sanz-García David Garcia AzorinJaime Samuel Rodríguez-VicoAlex JaimesAndrea Gómez GarcíaJavier Díaz de TeránNuria González-GarcíaSonia QuintasRocío BelascoaínJavier Casas LimónGermán LatorreCarlos Calle de MiguelÁlvaro Sierra Ángel Luis Guerrero-PeralCristina Trevino-PeinadoAna Beatriz Gago-Veiga

Published in: European journal of neurology (2022)

Our results show that ML models can predict anti-CGRP response at 6, 9 and 12 months. This study provides a predictive tool that can be used in a real-world setting.

Keyphrases

machine learning
copy number
dna methylation
deep learning
big data
binding protein