Novel loss-of-function mutations in TNFAIP3 gene in patients with lupus nephritis.

Changming ZhangXu HanLi SunSi-Rui YangJiahui PengYinghua ChenYing JinFeng XuZhi-Hong LiuQing Zhou

Published in: Clinical kidney journal (2022)

Kidney involvement may be the main feature of the clinical spectrum of HA20, even in adults. Genetic screening should be considered for early-onset LN patients.

Keyphrases

early onset
end stage renal disease
late onset
ejection fraction
genome wide
chronic kidney disease
newly diagnosed
copy number
prognostic factors
peritoneal dialysis
gene expression
dna methylation