Identification of New, Translatable ProtectomiRs against Myocardial Ischemia/Reperfusion Injury and Oxidative Stress: The Role of MMP/Biglycan Signaling Pathways.
Tamara SzabadosArnold MolnárÉva KenyeresKamilla GömöriJudit PipisBence PósaAndrás MakkosBence AggZoltán GiriczPéter FerdinandyAnikó GörbePéter BencsikPublished in: Antioxidants (Basel, Switzerland) (2024)
Our findings highlight 24 miRNAs that potentially regulate cardioprotective therapeutic targets associated with MMPs and BGN in a highly translatable porcine model of acute myocardial infarction.
Keyphrases
- ischemia reperfusion injury
- oxidative stress
- acute myocardial infarction
- left ventricular
- signaling pathway
- induced apoptosis
- percutaneous coronary intervention
- dna damage
- diabetic rats
- pi k akt
- bioinformatics analysis
- cell migration
- acute coronary syndrome
- coronary artery disease
- endoplasmic reticulum stress
- atrial fibrillation
- heat shock