Enhanced Cardiomyocyte NLRP3 Inflammasome-Mediated Pyroptosis Promotes d-Galactose-Induced Cardiac Aging.

Wen-Bin LiuSui-Sui WangXu ZhangZe-Zhi KeXiu-Yun WenJie ZhaoXiao-Dong Zhuang Li-Zhen Liao

Published in: Journal of the American Heart Association (2024)

The reactive oxygen species/nuclear factor κ-light-chain enhancer of activated B cells/NLRP3 signaling pathway loop contributes to d-galactose-treated cardiomyocyte senescence and cardiac aging.

Keyphrases

nlrp inflammasome
nuclear factor
high glucose
reactive oxygen species
endothelial cells
signaling pathway
toll like receptor
left ventricular
transcription factor
angiotensin ii
dna damage
diabetic rats
epithelial mesenchymal transition
immune response
binding protein
newly diagnosed
induced apoptosis