Qualitative analysis of the acetogenins from Annona coriacea (Annonaceae) leaves by HPLC-Q-Orbitrap and their antibacterial potential against oral pathogens.
Ana Paula TerezanJoão Gabriel M JunqueiraVinícius G WakuiLucilia KatoCecília Maria A OliveiraCarlos Henrique Martins da SilvaMariana B SantiagoVanessa Gisele P SeverinoPublished in: Natural product research (2020)
Araticum is an edible and appreciable fruit of Annona coriacea, which is popularly known as a traditional herb in the Brazilian cerrado. A phytochemical study from the leaves of A. coriacea showed that HPLC-ESI-Q-Orbitrap® provided through PRM experiments (MS2) is an efficient method for the fast and accurate analysis of a complex mixture of annonaceous acetogenins, with the identification of sylvaticin and gigantetrocin-A type acetogenins for the first time. In addition, the crude leaf extract and acetogenin-rich fractions were assayed against Streptococcus mutans, S. mitis, S. sanguinis and S. salivarius strains, which are usually related to oral infections.
Keyphrases
- ms ms
- mass spectrometry
- ultra high performance liquid chromatography
- high resolution
- tandem mass spectrometry
- simultaneous determination
- liquid chromatography
- high performance liquid chromatography
- biofilm formation
- candida albicans
- high resolution mass spectrometry
- essential oil
- escherichia coli
- gas chromatography
- solid phase extraction
- multiple sclerosis
- risk assessment
- cystic fibrosis
- silver nanoparticles